Search results for " shrinkage"

Eutrophic status influences the impact of pesticide mixtures and predation on Daphnia pulex populations

2021

Abstract Pesticides, nutrients, and ecological stressors such as competition or predation co‐occur in freshwater ecosystems impacted by agriculture. The extent to which combinations of these stressors affect aquatic populations and the role of nutrients availability in modulating these responses requires further understanding. In this study, we assessed how pesticides affecting different taxonomic groups and predation influence the response of Daphnia pulex populations under different trophic conditions. An outdoor experiment was designed following a factorial design, with the insecticide chlorpyrifos, the herbicide diuron, and the predation by Notonecta sp. individuals as key stressors. Th…

Relation of early tumor shrinkage (ETS) observed in first‐line treatment to efficacy parameters of subsequent treatment in FIRE‐3 (AIOKRK0306)

2016

We explored the association of early tumor shrinkage (ETS) and non-ETS with efficacy of first-line and consecutive second-line treatment in patients with KRAS wild-type metastatic colorectal cancer treated in FIRE-3. Assessment of tumor shrinkage was based on the sum of longest diameters of target lesions, evaluated after 6 weeks of treatment. Shrinkage was classified as ETS (shrinkage by ≥ 20%), mETS (shrinkage by 0 to20%), mPD (minor progression0 to20%) and PD (progression ≥20%). Overall survival (OS) was 33.2 (95% CI 28.0-38.4) months in ETS patients, while non-ETS was associated with less favorable outcome (mETS 24.0 (95% CI 21.2-26.9) months, mPD 19.0 (95% CI 13.0-25.0) months, PD 12.8…

Surgical Treatment in Symptomatic Chiari Malformation Type I: A Series of 25 Adult Patients Treated with Cerebellar Tonsil Shrinkage

2019

Background: The variety of symptoms and radiological findings in patients with Chiari malformation type I makes both the indication for surgery and the technical modality controversial. We report our 5-year experience, describing our technique and critically evaluating the clinical results. Methods: Between 2012 and 2016, 25 patients (15 female and 10 male; mean age 39.2 years) underwent posterior fossa decompression for Chiari malformation type I. Their clinical complaints included headache, nuchalgia, upper limb weakness or numbness, instability, dizziness and diplopia. Syringomyelia was present in 12 patients (48%). Suboccipital craniectomy was completed in all cases with C1 laminectomy …

Muscle activity patterns and spinal shrinkage in office workers using a sit–stand workstation versus a sit workstation

2016

Reducing sitting time by means of sit-stand workstations is an emerging trend, but further evidence is needed regarding their health benefits. This cross-sectional study compared work time muscle activity patterns and spinal shrinkage between office workers (aged 24-62, 58.3% female) who used either a sit-stand workstation (Sit-Stand group, n = 10) or a traditional sit workstation (Sit group, n = 14) for at least the past three months. During one typical workday, muscle inactivity and activity from quadriceps and hamstrings were monitored using electromyography shorts, and spinal shrinkage was measured using stadiometry before and after the workday. Compared with the Sit group, the Sit-Stan…

Autocorrelation Metrics to Estimate Soil Moisture Persistence From Satellite Time Series: Application to Semiarid Regions

2021

Satellite-derived soil moisture (SM) products have become an important information source for the study of land surface processes in hydrology and land monitoring. Characterizing and estimating soil memory and persistence from satellite observations is of paramount relevance, and has deep implications in ecology, water management, and climate modeling. In this work, we address the problem of SM persistence estimation from microwave sensors using several autocorrelation metrics that, unlike traditional approaches, build on accurate estimates of the autocorrelation function from nonuniformly sampled time series. We show how the choice of the autocorrelation estimator can have a dramatic impac…

Automatic Processing Scheme for Low Laser Invasiveness Electro Optical Frequency Mapping mode

2016

International audience; Electro optical techniques are efficient backside contactless techniques usually used for design debug and defect location in modern VLSI. Unfortunately, the signal to noise ratio is quite low and depends on laser power with potential device stress due to long acquisition time or high laser power, especially in up to date technologies. Under these conditions, to maintain a good signal or image quality, specific signal or image processing techniques can be implemented. In this paper, we proposed a new spatial filtering by stationary wavelets and contrast enhancement which allows the use of low laser power and short acquisition time in image mode.

Influence of cavity type and size of composite restorations on cuspal flexure

2006

Objectives: The present study examines the influence of cavity type, and size of composite restorations on cuspal flexure due to polymerization shrinkage. Methods: Thirty healthy premolars were selected and divided into two experimental groups. Group 1: Mesial, mesiodistal, and MOD cavities were successively prepared in each tooth by means of the SONICSYS approx system (KaVo ®) using a nº 2 (small) diamond tip. Group 2: The same cavity preparation sequence was followed but a nº 3 (medium) tip was used. Cavity preparations were performed and afterwards restored using the same adhesive system and resin composite. Cuspal displacement was measured 15 min after completion of each type of restora…

Discussion of “Soil Water Retention Characteristics of Vertisols and Pedotransfer Functions Based on Nearest Neighbor and Neural Networks Approaches …

2013

Imidazo[2,1-b] [1,3,4]thiadiazoles with antiproliferative activity against primary and gemcitabine-resistant pancreatic cancer cells

2020

A new series of eighteen imidazo [2,1-b] [1,3,4]thiadiazole derivatives was efficiently synthesized and screened for antiproliferative activity against the National Cancer Institute (NCI-60) cell lines panel. Two out of eighteen derivatives, compounds 12a and 12h, showed remarkably cytotoxic activity with the half maximal inhibitory concentration values (IC50) ranging from 0.23 to 11.4 μM, and 0.29–12.2 μM, respectively. However, two additional compounds, 12b and 13g, displayed remarkable in vitro antiproliferative activity against pancreatic ductal adenocarcinoma (PDAC) cell lines, including immortalized (SUIT-2, Capan-1, Panc-1), primary (PDAC-3) and gemcitabine-resistant (Panc-1R), elici…

A new tuning parameter selector in lasso regression

2019

Penalized regression models are popularly used in high-dimensional data analysis to carry out variable selction and model fitting simultaneously. Whereas success has been widely reported in literature, their performance largely depend on the tuning parameter that balances the trade-off between model fitting and sparsity. In this work we introduce a new tuning parameter selction criterion based on the maximization of the signal-to-noise ratio. To prove its effectiveness we applied it to a real data on prostate cancer disease.